Welcome to the Mitochondrial Metabolism and Bioenergetics Laboratory! Our group studies how energy metabolism and metabolic flexibility – the ability to switch between sugar, amino acid, and fatty acid oxidation in response to biological cues – can control cell function and fate. Ultimately, we aim to discover novel regulatory points of metabolism and develop mitochondrial proteins and pathways as therapeutic drug targets.
Mitochondrial Methods Roadmap Published
Cheers to first-author Anthony and co-authors Aracely and Li (UCLA Pharmacology rotation student) on publication of their manuscript “Forces, fluxes, and fuels: tracking mitochondrial metabolism by integrating measurements of membrane potential, respiration, and metabolites” in American Journal of Physiology – Cell Physiology
It Only Took Us 4+ Years to Make a Website!
What have we missed…Brandon Desousa and Kristen Kim both joined the lab as research associates (2017) and left (2019) to pursue graduate studies at UCSF (Brandon) and Yale (Kristen). Anthony Jones (2018) and Aracely Acevedo (2020) joined the laboratory as Ph.D. students. Both earned a Cota-Robles Scholarship, and Anthony was the recipient of T32 fellowship from the UCLA Tumor Cell Biology Training Grant. Krista Yang joined our group as a laboratory manager (2020) after graduating from UCLA and working with Dr. Cathy Clarke as an undergraduate. Our lab has been fortunate to receive grant support from a sponsored-research agreement with AstraZeneca (2019), pilot awards from the UCLA-UCSD Diabetes Research Center (2020) and the UCLA SPORE in Prostate Cancer (2020), as well as an NIH NIGMS R35 MIRA award (2020).